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chicken pot pie bubble up casserole in a white baking dish

Chicken Pot Pie Bubble Up Casserole Recipe

This Chicken Pot Pie Bubble Up is the ultimate comfort food that will satisfy your hunger. With its creamy filling, golden biscuits, and hearty combination of chicken, vegetables, and cheese, it's a dish the whole family will love.
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Course: Chicken
Cuisine: American
Prep Time: 10 minutes
Cook Time: 35 minutes
Total Time: 45 minutes
Servings: 8 servings
Calories: 335kcal
Author: Jennifer Stewart

Equipment

Ingredients

  • 2 ½ cups cooked chicken diced or shredded
  • 1 10.5 ounce can cream of chicken soup
  • 8 ounces sour cream
  • 1 teaspoon garlic powder
  • ½ teaspoon onion powder
  • 2 cups frozen mixed vegetables
  • 2 cups shredded cheddar cheese
  • 1 12 ounce can refrigerated biscuits (10 count)

Instructions

  • Preheat oven to 350F. Prepare a 9x13 baking dish with nonstick spray
  • In a large mixing bowl, combine the chicken, soup, sour cream, garlic and onion powder.
  • Stir to combine.
  • Fold in the mixed vegetables and cheddar cheese.
  • Cut the biscuits into quarters.
  • Fold the pieces into the chicken mixture gently.
  • Spread into the prepared 9x13 pan.
  • Bake for 35-45 minutes or until bubbly and the biscuits are golden brown.
  • Remove and let cool for 2-3 minutes to set up. Serve warm.

Notes

  • Incorporate ½ the biscuit pieces into the mix and scatter the remaining ones on top for more of a crust look.
  • I prefer the regular biscuits but you can use the larger ones. Might need to cut them into 6 pieces so they cook evenly.
  • Flaky layers or homestyle are the best texture. Buttermilk biscuits work well too.
  • Add extra cheese if you love cheese!
  • Substitute cream cheese for the sour cream.
  • Try different cream or condensed soups for more flavor.
  • Add different seasonings to change the flavor profile.
  • Use canned or rotisserie chicken. Can use chicken thighs if desired. I have not tested this using raw chicken.
  • Canned vegetables are a quick option but might become mushy during the baking.
  • If you only have fresh vegetables, blanch or steam them before adding to the casserole.

Nutrition

Serving: 1g | Calories: 335kcal | Carbohydrates: 13g | Protein: 20g | Fat: 23g | Saturated Fat: 10g | Polyunsaturated Fat: 9g | Cholesterol: 86mg | Sodium: 394mg | Fiber: 2g | Sugar: 3g